Margarita Irizarry-Ramírez, Ph D.

PhD in Biochemistry and Molecular Biology
MS in Molecular Biology of Radiation
BS in Biology

Academic Coordinator of the Master in Clinical Laboratory Science Program
Chair of Institutional Review Board (IRB) panel
Chair of the Curriculum Committee of the Post Doctoral Master in Clinical Research Program

Dr. Margarita Irizarry has taught Biology, Molecular Biology and Biochemistry at the undergraduate and graduate levels. Presently she teaches at the graduate level in the Clinical Laboratory Science Program and in the Post Doctoral Master in Clinical Research Program.

She also teaches third year Medical Students a lecture on the Introduction to Medical Ethics: Constraints and Consequences.

Dr. Irizarry has been Science Department Chair and Associate Dean for Science. She has received grants from the National Science Foundation and the Department of Education to create programs to increase the number of minority students entering graduate school to pursue careers in Science, Mathematics and Engineering. Presently she has grants to study Molecular Biology and Protein Biology of Prostate cancer and leukemia

1. Roots,R., Holley,W., Chatterjee,A.,Irizarry,M.,and Kraft,G. “The Formation of Strand Breaks in DNA After High-LET Irradiation: A Comparison of Data From In Vitro and Cellular Systems”. Int. Rad. Biol. 1990 58: 55-70

2. Concerted gene expressions in elicited fibroin synthesis”. G.C.Candelas,G,Arroyo,C.Carrasco,E.Carrasquillo, A.Plazaola and M.Irizarry Chap. 12 in Translational Regulation of Gene Expression 2. ed.J.Ilan. Plenum Press 1993

3. Irizarry-Ramírez,M, Ríos,W and Rodríguez Medina J.R.“Increased expression of SWE1 mRNA suggests an activation of a morphogenesis checkpoint in type-II myosin deficient Saccharomyces cerevisiae”. 2000 MiamiNat. Biotec. 11

4. El cáncer y el ciclo celular.2000 Hola M.T. 16:8-10

5. Willson,C.,Irizarry-Ramírez,M.,Cruz-Orengo,L., Figueroa,J., Whittemore,S., Miranda,J.D.

Upregulation of EphA Receptor Expression in the Injured Adult Spinal Cord. Cell Transplantation 2002 11:229-239

6. Ríos Muñoz, W., Irizarry-Ramírez,M., Rivera Molina, F., González Crespo, S, Rodriguez-Medina, J. Myosin II is important for maintaining regulated secretion and asymmetric localization of Chitinase 1 in the budding yeast Saccharomyces cerevisiae.2003 Arch.Bioch.Biophys 409(2):411-3

Abstracts and Poster Presentations

1. Homeobox containing Genes in Mammary Gland Development and Remodeling. A.Srebrow, Y Friedman,P.Strickland, M.Irizarry, C.W.Daniel y M.J.Bissell 1995 Mol. Biol. Cell 6:59

2. Cell cycle dynamics in yeast support that type II myosin may function in multiple cell cycle stages. Irizarry-Ramírez,M.,Ríos,W.Gómez,D.González, S y Rodríguez-Medina J.R 1999 .Mol Biol Cell 10: Suppl.pp.194

3. Upregulation of the receptors Tyrosine Kinases EphA3 and EphA4 after Spinal Cord Injury.

Irizarry-Ramírez,M.,Willson,C.,Cruz,L,Whittemore, S. y Miranda, J.D. 2000 Mol.Biol. Cell.

11: Suppl:pp:474

4. EphA expression after contusive spinal cord injury . Irizarry-Ramírez, M., Willson, C., Cruz,L.,

Foster, R. Whittemore, S. and Miranda J.2001 Proceedings of the First Conference of Specialized Centers for Neuroscience

5. Eph and ephrin expression after spinal cord injury. Whittemore, S.R., Willson,C., Irizarry, M., Cruz,L.,Miranda,JD. 2001 American Society for Neural Transplantation

6. In adult rats the expression of EphA3 a protein tyrosine kinase receptor is induced after spinal cord injury. Irizarry-Ramírez, M., Willson, C., Foster, R. Whittemore, S. and Miranda 2001 31^{st.Annual meeting of Society for Neuroscience}

^{7.  Frequency of Hepatitis C Virus and Human Immunodeficiency Virus-! In Donated Blood in Puerto Rico. Enríquez, M., Rodríguez-Orengo, J.F., Torres,E., Irizarry, M. and Rodríguez-Medina J.R.2002 8th Annual RCMI Symposium}

8. RT-PCR determination of the expression of the fusion gene t15,17 in promyelocytic leukemia patients. J. Salgado, A. López Enríquez and M. Irizarry-Ramírez. 2004 Interamerican Society of Heamtology.

9. Isoformas del gene de fusión PML-RARα parecen modular la respuesta del paciente de Leucemia Promielocítica Aguda al tratamiento con Acido Retinoico. J. Salgado. A. López, M. Irizarry-Ramírez. 2005. XXV Foro Anual de Investigación y Educación Recinto de Ciencias Médicas

American Society for Cell Biology
American Association for the Advancement of Science (President Elect of the Caribbean Division)
Clinical Ligand Assay Society
Radiation Research Society
Applied Research Ethics National Association (ARENA)

1. RCR II Grant #1P20RR11126 .
2. NCI Grant U54# RFA-CA-02-
3. RCMI Grant #G12RR03051
4. MBRS-SCORE S06GM008224